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Sukesh Voruganti Selected Research

Neoplasms (Cancer)

10/2020Tumor-Activated Benzothiazole Inhibitors of Stearoyl-CoA Desaturase.
10/2018Discovery and Characterization of Dual Inhibitors of MDM2 and NFAT1 for Pancreatic Cancer Therapy.
7/2016Identification of lineariifolianoid A as a novel dual NFAT1 and MDM2 inhibitor for human cancer therapy.
12/2015RYBP predicts survival of patients with non-small cell lung cancer and regulates tumor cell growth and the response to chemotherapy.
11/2015Polycomb Group (PcG) Proteins and Human Cancers: Multifaceted Functions and Therapeutic Implications.
10/2015Inhibiting NFAT1 for breast cancer therapy: New insights into the mechanism of action of MDM2 inhibitor JapA.
8/2015Oral nano-delivery of anticancer ginsenoside 25-OCH3-PPD, a natural inhibitor of the MDM2 oncogene: Nanoparticle preparation, characterization, in vitro and in vivo anti-prostate cancer activity, and mechanisms of action.
7/2015Development and validation of an HPLC-MS/MS analytical method for quantitative analysis of TCBA-TPQ, a novel anticancer makaluvamine analog, and application in a pharmacokinetic study in rats.
5/2015Development and validation of a rapid HPLC method for quantitation of SP-141, a novel pyrido[b]indole anticancer agent, and an initial pharmacokinetic study in mice.
2/2015Identification of a new class of natural product MDM2 inhibitor: In vitro and in vivo anti-breast cancer activities and target validation.
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Sukesh Voruganti Research Topics

Disease

15Neoplasms (Cancer)
10/2020 - 01/2012
6Breast Neoplasms (Breast Cancer)
05/2016 - 01/2012
3Neoplasm Metastasis (Metastasis)
10/2018 - 01/2012
3Pancreatic Neoplasms (Pancreatic Cancer)
10/2018 - 05/2012
1Ulcerative Colitis
11/2017
1Lung Neoplasms (Lung Cancer)
12/2015
1Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
12/2015
1Prostatic Neoplasms (Prostate Cancer)
08/2015
1Hepatocellular Carcinoma (Hepatoma)
11/2014
1Carcinogenesis
06/2013

Drug/Important Bio-Agent (IBA)

3Proteins (Proteins, Gene)FDA Link
05/2016 - 10/2014
3Biomarkers (Surrogate Marker)IBA
12/2015 - 06/2013
3Biological ProductsIBA
02/2015 - 01/2012
2GinsenosidesIBA
08/2015 - 01/2012
225-methoxylprotopanaxadiolIBA
08/2015 - 01/2012
2Antineoplastic Agents (Antineoplastics)IBA
07/2015 - 06/2013
26- methoxy- 1- (naphthalen- 1- yl)- 9H- pyrido(3,4- b)indoleIBA
05/2015 - 10/2014
1Stearoyl-CoA DesaturaseIBA
10/2020
1ProdrugsIBA
10/2020
1benzothiazoleIBA
10/2020
1BenzothiazolesIBA
10/2020
1Cytochrome P-450 Enzyme System (Cytochrome P450)IBA
10/2020
1GemcitabineFDA Link
10/2018
1MA242IBA
10/2018
1Oncogene Proteins (Oncogene Protein)IBA
10/2018
1Dinoprostone (PGE2)FDA Link
11/2017
1SW033291IBA
11/2017
115-hydroxyprostaglandin dehydrogenaseIBA
11/2017
1Transcription Factors (Transcription Factor)IBA
05/2016
1polyethylene glycol-poly(lactide-co-glycolide)IBA
08/2015
1iminoquinoneIBA
07/2015
1Proto-Oncogene Proteins c-mdm2IBA
02/2015
1Cisplatin (Platino)FDA LinkGeneric
11/2014
1indoleIBA
10/2014
1Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA
10/2014
1Therapeutic UsesIBA
10/2014
1SesquiterpenesIBA
10/2013
1MicroRNAs (MicroRNA)IBA
06/2013
17- (4- fluorobenzylamino)- 1,3,4,8- tetrahydropyrrolo(4,3,2- de)quinolin- 8(1H)- oneIBA
05/2012

Therapy/Procedure

10Therapeutics
10/2018 - 01/2012
2Drug Therapy (Chemotherapy)
12/2015 - 11/2014
1Hepatectomy
11/2017
1Bone Marrow Transplantation (Transplantation, Bone Marrow)
11/2017
1Intraperitoneal Injections
10/2014